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In 1891, it was found to be useful to treat malaria, thus making methylene blue "the first synthetic compound ever used as an antiseptic in clinical therapy and the first antiseptic dye to be used therapeutically," according to the authors of a Medicinal Research Reviews paper on the compound

doi: 10.1016/j.biopha.2020.110108 61 KobayashiSHamashimaSHommaTSatoMKusumiRBannaiSet al

It can, but it does not have to

Taking glutathione has many potential benefits, including: Reducing oxidative stress Reducing cell damage in alcoholic and nonalcoholic liver disease Improving insulin resistance in older people Increasing mobility for people with peripheral artery disease Reducing symptoms of Parkinsons disease Helping combat autoimmune diseases Minimizing oxidative damage in children with autism Reducing the impact of uncontrolled diabetes Countering respiratory disease symptoms Might improve psoriasis Does glutathione help reduce oxidative stress

The samples were vacuum-dried and stored at 80 C until further analysis