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Concomitant use with nitroglycerin can lead to increased blood levels of nitroglycerin, causing a severe drop in blood pressure

10.1002/jor.24529 J

N Engl J Med 384:205215 Kanter J, Telen MJ, Hoppe C, Roberts CL, Kim JS, Yang X (2015) Validation of a novel point of care testing device for sickle cell disease

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Oxidative stress may contribute to processes involved in cardiovascular disease, including endothelial dysfunction, LDL oxidation, inflammation, mitochondrial injury, and plaque formation