Ethical prescribing and supply management We operate across the whole of Ireland as a digital healthcare service and are acutely aware of the national supply pressures that have affected the availability of these medicines, particularly for patients with Type 2 diabetes

Practical management strategies include: Taking tirzepatide at a consistent time each week, preferably when you can rest if side effects occur Following the prescribed dose escalation schedule without rushing increases Keeping a food and symptom diary to identify potential dietary triggers Using over-the-counter antidiarrheal medications like loperamide (Imodium) for occasional relief, after consulting your healthcare provider (avoid if you have fever or bloody stools, and do not exceed recommended dosing) Considering probiotics, though evidence for their effectiveness specifically with GLP-1 receptor agonist-related diarrhea remains limited Patients should not discontinue tirzepatide without medical guidance, as gastrointestinal symptoms often improve with continued use
The reconstituted solution requires refrigeration and careful handling to maintain potency
While both are growth-related peptides, they function very differently in the body with distinct implications for muscle hypertrophy, fat loss, recovery, and long-term performance goals
This guide explains what to do, which symptoms to watch for, and when to seek urgent medical help