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What the Clinical Evidence Says About the Combination A randomized controlled trial published in the Journal of Cutaneous and Aesthetic Surgery comparing dermaroller monotherapy versus dermaroller combined with copper peptide for acne scars across 16 weeks produced findings that are clinically useful but deserve an honest reading

Quaranta A, Scaringi A, Bartoli R, Margarito MA, Quaranta N

Bibcode:2009PNAS..106.1285L

Early studies have demonstrated that erythrocytes possess caspase-3 and caspase-8 and can die via an apoptotic-like cell death triggered by Ca 2+ ionophores

CCK8 results showed that the three hydrogels did not cause significant cellular toxicity on day 3 or day 5 (Figure S7)