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Varicocele repair also can increase testosterone levels, although rigorous data supporting its use remain lacking

Clinical trials back this up: the STEP trials showed an average weight reduction of around 15% with Semaglutide, while the SURMOUNT trials reported up to 20% with Tirzepatide

Archived from the original on October 16, 2014

For context, weekly semaglutide produced ~15% placebo-adjusted weight loss at 68 weeks in STEP 1, weekly tirzepatide produced ~21% at 72 weeks in SURMOUNT-1, and retatrutide hit 28.7% at 68 weeks in TRIUMPH-4