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Results The model was validated by demonstrating that the profile of effects on chemiluminescence of acetic acid induced colitis biopsy specimens given by conventional antioxidants (sodium azide, catalase, copper-zinc superoxide dismutase, dimethyl sulphoxide, N-acetylcysteine and ascorbate) and standard therapies (5-aminosalicylate and hydrocortisone) resembled that previously reported using biopsy specimens from ulcerative colitis

Trimetazidine protects cardiomyocytes against hypoxia-induced injury through ameliorates calcium homeostasis

A very rapid onset could be linked to side effects like nausea or flushing

Stratification across the treatment groups was based on gender