tirzepatide and mash Newly released phase IIb 48-week liver biopsy data on #tirzepatide in #MASH. 73.9% resolution of with no worsening of fibrosis on 15 mg. Secondary endpoint ⬇️ fibrosis by >1 stage Lilly's Tirzepatide Improves Liver Fibrosis

Safe Alternatives and Evidence-Based Weight Loss Strategies For individuals seeking effective weight management, several evidence-based alternatives exist that do not involve combining multiple prescription medications

Dalrymple LS, Katz R, Kestenbaum B, et al

Identifying and limiting gas-producing foods that may worsen symptoms is helpful

Semaglutide (Compounded): A GLP-1 receptor agonist that helps reduce appetite, slow digestion, and regulate blood glucose levels

The combined rise in cytosolic Ca and possible PKC activation may modulate downstream transcriptional programs, thereby supporting growth hormone synthesis and its pulsatile secretion from somatotroph cells