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Research suggests that NNMT inhibition may influence metabolic pathways related to energy expenditure, fat metabolism, and cellular vitality

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NNMT catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM, the universal methyl donor in cells) to nicotinamide (a form of vitamin B3 and a precursor for NAD+ synthesis), producing 1-methylnicotinamide and S-adenosylhomocysteine (SAH)

Doctors might also need to adjust how much and how often to give it, based on each patients needs