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Note that if your dog has been diagnosed with inflammatory bowel disease (IBD) or another chronic GI disorder, treatments for that underlying condition may not be effective until a healthy B12 level has been restored

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Certain medications such as Metformin, H2-receptor antagonists including Zantac (Ranitidine), Tagamet(Cimetedine), Famotidine, Pepcid AC (Oral Pepcid), Axid AR (Nizatidine), Proton pump inhibitors (PPIs)including Prilosec (Omeprazole), Nexium (Esomeprazole), Prevacid (Lanzoprazole) and Antacids e.g:Gaviscon can also affect your ability to absorb vitamin B12