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Finally, the AMPLITUDE-O trial, which included patients with T2D and either a history of CVD (90%) or CKD, demonstrated that efpeglenatide significantly reduced MACE by 27% (HR 0.73

Expert Opin Pharmacother 2023;24:58797

And the patient population is more price-sensitive, which limits how much manufacturers can charge

The gene is found in hypothalamic cells and produces a polypeptide that forms various kisspeptin sequences, which are key to regulating reproductive hormones [22, 23]

Dobritzsch D, Wang H, Schneider G, Yu S (2014) Structural and functional characterization of ochratoxinase, a novel mycotoxin-degrading enzyme