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3 physiological reasons hunger can increase after taking a GLP-1 1

This small pilot study, evidently, requires repetition with a much larger number of volunteers and a prolonged observational period

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Adding MOTS-c to an insulin regimen could increase the risk of hypoglycemia (low blood sugar)

Blood 93:28672875 Wang WL, Kasamatsu J, Joshita S, Gilfillan S, Di Luccia B, Panda SK, Kim DH, Desai P, Bando JK, Huang SC et al (2022) The aryl hydrocarbon receptor instructs the immunomodulatory profile of a subset of Clec4a4(+) eosinophils unique to the small intestine