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Additionally, inhibition of CD38 in the AD mouse model restored NAD + levels, decreased mitochondrial ROS production and plaque depositions in the hippocampus and cortex, and improved cognitive abilities 158

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doi: 10.3389/fpsyt.2024.1421150 Received 21 April 2024 Accepted 26 August 2024 Published 23 September 2024 Volume 15 - 2024 Edited by Mirko Manchia, University of Cagliari, Italy Reviewed by Donatella Marazziti, University of Pisa, Italy Maryam Pourshams, Ahvaz Jundishapur University of Medical Sciences, Iran Irene Martnez-Garca, University of Castilla La Mancha, Spain Updates Copyright 2024 Eghdami, Eissazade, Heidari Mokarar, Boroon, Orsolini and Shalbafan

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