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Their latest game-changing study, published in the prestigious Cell Metabolism, reveals a critical link between aging, obesity, and metabolismand a natural solution hiding in your fruit bowl: fisetin , a plant-based compound found in strawberries, apples, and onions
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One interesting study used a network pharmacology approach to show that the TCM herb pair Gui ZhiShao Yao (Cinnamomum cassia & Paeonia lactiflora) may treat chronic pain with cooccurring anxiety and depression through 15 active compounds acting on 130 targets, with nine core proteins (including Akt1, IL6, TNF, PTGS2, and PPAR) and 11 key inflammatory and stress-related pathways (such as AGERAGE, IL17, and TNF signaling), suggesting a multi-target, systems-level mechanism that still needs confirmation in experimental models
