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These findings underscore the complex role of AKR1C3 in gynecological malignancies and its potential as a prognostic indicator in specific subtypes of endometrial and cervical cancers
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Emerging evidence indicates that vitamin D, through receptor-mediated signaling, participates in multiple pathophysiological processes, including the regulation of immune and inflammatory responses, the mitigation of oxidative stress, the preservation of mitochondrial function, the inhibition of renal fibrosis, modulation of the reninangiotensinaldosterone system (RAAS), and the maintenance of gutkidney axis homeostasis
Eur J Pharmacol (2012) 674(2-3):2806