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Best practice requires three control groups at minimum: an untreated control, a copper-free GHK tripeptide control (isolating the peptides contribution), and an equimolar CuSO4 control (isolating coppers contribution)

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What You Should Know About MOTS-c MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a 16-amino-acid peptide encoded by the human mitochondrial genome