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A first-in-human study to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of KM-819 (FAS-associated factor 1 inhibitor), a drug for Parkinson’s disease, in healthy volunteers

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do Vale et al, 2020 do Vale GT, Leoni D, Sousa AH, Gonzaga NA, Uliana DL, La Gata DC, Resstel LB, Padovan CM, Tirapelli CR (2020) Acute restraint stress increases blood pressure and oxidative stress in the cardiorenal system of rats: a role for AT1 receptors