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Biol Chem 378:793802 Crack PJ, Taylor JM, Flentjar NJ, de Haan J, Hertzog P, Iannello RC, Kola I (2001) Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury
Liraglutide should be discontinued in patients who cannot tolerate the maximum dose, as well as in those who have not lost 4% of their baseline body weight by 16 weeks after initiating therapy, since continued treatment is unlikely to result in additional weight-loss benefit