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Preclinical studies demonstrate that GLP-1RAs reduce vascular inflammation through multiple mechanisms, including decreased nuclear factor-B activation, reduced expression of adhesion molecules, and diminished macrophage infiltration in vessel walls

[DOI] [PMC free article] [PubMed] [Google Scholar] 232.Shao J., Wang B., Li J., Jansen J.A., Walboomers X.F., Yang F

During the acute phase of the virus, the immune system launches a massive inflammatory response, generating enormous amounts of reactive oxygen species (ROS) to destroy the invading pathogen