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These findings underscore the potential of PDHA1 inhibition to counteract Enz resistance by reactivating cuproptosis, offering a promising therapeutic approach for treating refractory prostate cancer
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Immunohistochemical analysis of biopsy and postmortem samples revealed increased expression of UPR markers, including CHOP and BiP, in oligodendrocytes, astrocytes, T cells, and macrophages/microglia within MS lesions
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Nat Rev Immunol 2006
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