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We confirmed a strong inverse correlation between beta cell mass and glucose intolerance, consistent with clinical observations that OGTT or continuous glucose monitoring (CGM)-derived metrics can predict symptomatic onset in at-risk individuals once beta cell loss has crossed a critical threshold required for metabolic control [66]

Clinicians are unprepared, which is why health systems need to prioritise training, early identification, and finding a better way to reduce harm in young people, he said

In animal models of diabetic nephropathy, a dose of curcumin equivalent to about 1.1 g for an adult human prevented the progression of renal disease (Trujillo 2013)

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Pooled analysis including these two studies in addition to SELECT and FLOW [31] reported that semaglutide reduced the risk of hospitalization or urgent visits due to heart failure by 41% (HR 0.59, 95% CI 0.410.82) in HFpEF patients compared with placebo [32]