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This has led to interest in NAC for conditions like systemic lupus erythematosus (SLE), where a small RCT found that NAC (2.4-4.8 g/day) improved disease activity scores and reduced anti-dsDNA antibody levels (Lai et al., Lupus, 2012) [42]

Under normal circumstances, fatty acid hydroperoxides can be converted into fatty acid alcohols through GPX4 mediation (72)

Next, the binding sites between miR-155-5p and PAK2 were predicted using the miRNA-Target (mRNA) option

Osmolality was chosen as the parameter for normalisation, since the creatine concentrations differed between the two groups, while osmolality was much more consistent (Supplementary Fig

T2DM is associated with insulin resistance (IR)