These results suggest that the perturbation of GSTF11 and GSTU20 caused a wide range of cellular alterations likely result from the disrupted GSL biosynthesis
doi:10.1016/j.biochi.2012.10.008 Prasath GS, Subramanian SP (2013) Fisetin, a tetra hydroxy flavone recuperates antioxidant status and protects hepatocellular ultrastructure from hyperglycemia mediated oxidative stress in streptozotocin induced experimental diabetes in rats
however, the differences between the vitamin and placebo groups were not statistically different at any of the measured timepoints (3 months, 6 or 9 months, and 12 months) (103)
The study, Central nervous system uptake of intranasal glutathione in Parkinsons disease, was published in the journal NPJ Parkinsons Disease
But for the major therapeutic peptides used in aesthetic and longevity protocols, injectable delivery is the baseline for reliable results