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Ly LD, Xu S, Choi S-K, Ha C-M, Thoudam T, Cha S-K, et al
The structural collagen improvements are long-lasting, but skin continues to age and new stretching forces can create new marks
62 , e202217448 (2023)
doi: 10.1096/fsb2fasebj.12.1.57 162 GruenMLHaoMPistonDWHastyAH
Erectile function improvements How PT-141 helps erections: Improves erectile quality (firmness) Increases ability to achieve erection Sustains erection longer Works for mild-moderate ED Particularly effective for psychological ED Expected results: 60-70% of men experience improved erections Not as powerful as Viagra for pure erectile function But works for cases where Viagra doesn't Better spontaneous erections (not just stimulation-dependent) Improved morning erections Who responds best: Men with psychological/performance anxiety ED Mixed psychological + physical ED Those who don't respond well to PDE5 inhibitors Men seeking enhanced desire (not just mechanical function) Libido and desire enhancement The desire component: Significantly increased sexual thoughts More spontaneous arousal Enhanced attraction to partner Better sexual interest and motivation Improved sexual confidence Subjective experiences men report: "Feel like I'm 20 again" Increased desire for initiating sex More intense arousal Better mental focus during sex Enhanced pleasure and sensation Timeline: Immediate: Increased interest (30-60 min) 2-4 hours: Peak desire and function 6-12 hours: Continued enhanced interest Next day: Slight residual effect possible Performance and satisfaction Sexual performance benefits: Reduced performance anxiety Better stamina Multiple erections in session possible Enhanced orgasm intensity (some men) Improved refractory period (time between erections) Partner satisfaction: More engaged, present during sex Increased initiation Better sustained performance Enhanced emotional connection Overall improved sexual experience Quality of life: Restored sexual confidence Better relationship satisfaction Reduced stress about performance Positive feedback loop (success confidence more success) PT-141 nasal spray vs injectable for men Comparing the two administration methods
