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Mechanisms of plaque stabilization with statins

Heres a chart, based on data from this study: People with obesity or metabolic syndrome have chronically high GLP-1 levels, possibly because the diet that tends to cause obesity and metabolic syndrome is high in sugar and simple carbs, which raise blood sugar and demand a lot of GLP-1

The gradual increase allows the body to develop tolerance to these effects while still building therapeutic benefit at each stage

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