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At the highest tested dose of 12mg weekly, participants lost an average of 24.2% of their baseline body weight

However, Novo Nordisk, Ozempics manufacturer, released results from two clinical trials in November 2025 that showed that taking an oral GLP-1 didnt slow disease progression among people with Alzheimers compared to those who took a placebo

As researchers continue to uncover the many roles of GLP-1, GLP-1R, and synthetic GLP-1RAs in systems beyond the endocrine, potential pharmacologic applications of GLP-1RAs in a variety of pathology are becoming increasingly clear