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However, in CRC-PDCO models, a high abundance of Fn was found to significantly enhance tumor sensitivity to PD-L1 blockade by promoting the infiltration of interferon-producing CD8 tumor-infiltrating lymphocytes (TILs), thereby improving the efficacy of ICIs [111]
Worth noting, L-carnitine that occurs naturally in food, mainly red meat, is absorbed far better than supplement doses, with dietary bioavailability reported as high as 75 percent
Accessed 21 Dec 2021
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