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If you use laxatives, including PEG 3350-based products, for a long period of time (over a period of weeks or months) then you may experience withdrawal symptoms if you stop taking them suddenly

Precipitating conditions for diabetic ketoacidosis or other ketoacidosis include under-insulinization due to insulin dose reduction or missed insulin doses, acute febrile illness, reduced caloric intake, ketogenic diet, surgery, volume depletion, and alcohol abuse

often referenced under its code name AM833 or related patent numbers

Topical effects Most reported topical effects are mild and local: redness, tingling, dryness, or transient irritation at the application site, typically more common with concentrations above 4%

Hair should appear normal during this period