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We found a significant increase in the plasma IL-1, IL-6, TNF-, IP-10, and liver-associated active phase proteins (CRP and SAA) in LC patients versus R and HCs ( Figures 6A-F )

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This data-driven foundation ensures that weight loss targets fat rather than precious muscle mass, and that treatment decisions are based on objective measurements rather than assumptions

Data from other groups and our recent study have shown that endothelium and cardiac and vascular myocytes express a functional GLP-1R, and participate in the protective cardiovascular effects of GLP-1 analogues 11,36,37,38