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Consequently, obese individuals have attenuated GH responses to GH secretagogues (68)

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Besides Gpx1, Gpx4 displays preference for lipid hydroperoxides ( Figure 3 ), and hence plays a key role in protecting phospholipids, cholesteryl esters and cardiolipin and defense against apoptosis and maintenance of ETC and OXPHOS ( + / - cells are sensitive to oxidative stress triggers (Legault et al., 2000

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