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CoQ10 supplementation has proven to be safe and well-tolerated even at high doses, but rare adverse effects such as nausea, vomiting, loss of appetite, and dyspepsia have been reported

Because reduced glutathione oxidizes readily once in solution, reconstituted material should be kept at 28C and used promptly to preserve the reduced (GSH) form

To understand why, we have to look at how the stomach handles proteins

A subsequent pilot study (n=12) comparing oral liposomal glutathione (500 mg twice daily for 2 weeks) found increases in GSH levels in whole blood, erythrocytes, and plasma, along with reductions in 8-isoprostane (a marker of oxidative stress) (Buonocore et al., Oxid Med Cell Longev, 2016) [16]