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B12 deficiency can happen for several reasons, including: If B12 deficiency is suspected, lab testing and medical guidance are important

Serious but rare complications: Hypokalaemia: Rapid B12 replacement in severely deficient patients can precipitate potassium depletion during haematopoietic recovery, potentially causing cardiac arrhythmias

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The research and formulation guidance converge on specific ranges that balance efficacy with safety

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