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Compared to NSAIDs: No gastrointestinal toxicity No cardiac risks No kidney damage risk No drug interactions Actively promotes healing rather than masking symptoms Compared to corticosteroids: No immunosuppression No bone density loss No endocrine disruption No adrenal suppression Promotes healing rather than suppressing inflammation Compared to other peptides: Similar or better safety profile Minimal side effects No hormonal disruption Well tolerated across populations Regulatory and Ethical Considerations Researchers should be aware of the regulatory status

Due to its effects as a competitive inhibitor of numerous 2-oxoglutarate and Fe 2+ -dependent dioxygenases, 2-HG is referred to as an oncometabolite

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The pandemic also created high levels of stress for many individuals, and stress can lead to weight gain