For BPC-157 , the deepest non-musculoskeletal literature is gastrointestinal: cytoprotection of the stomach lining, ulcer healing, and effects on fistula and anastomosis healing in rodents, tied mechanistically to the nitric-oxide system
Peptide Vials (NAD+, 500 mg each): 8 weeks 11 vials (total 5,075 mg used) 12 weeks 16 vials (total 7,875 mg used) 16 weeks 22 vials (total 10,675 mg used) Insulin Syringes (U100, 1 mL): Per week: 7 syringes (1/day) 8 weeks: 56 syringes 12 weeks: 84 syringes 16 weeks: 112 syringes Bacteriostatic Water (10 mL bottles): Use 3.0 mL per vial for reconstitution
The authors also reported a correlation between impaired permeability and lower nuclear ZO-1 staining, the importance of which is difficult to interpret because its normal localization should be at the level of the tight-junctions (142)
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Thus all of the DNA synthetic effects of B 12 deficiency, including the megaloblastic anemia of pernicious anemia, resolve if sufficient dietary folate is present