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To maximise area coverage, we have used two depths x burr hole, injecting 0.625 l per depth for a total of 1.25 l per burr hole (details in the Method section)

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MECOARK-2500 Injection should only be used under the supervision and prescription of a qualified healthcare professional

Vial Size: 3ml (can hold up to 3ml BAC water) Shelf Life: The lyophilized form has a shelf life of 24 months when properly stored

The promise of GLP-1s to address these concerns is understandably appealing, but we lack adequate research to guide evidence-based prescribing and patient decisionmaking for this population