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Patients taking medications that affect heart rate, particularly beta-blockers, calcium channel blockers, or antiarrhythmic drugs, should be identified, as these may modify the heart rate response to GLP-1 therapy

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doi:10.1016/j.biopsych.2008.04.022, PMID: 18534556 Magalhes PV, Dean OM, Bush AI, Copolov DL, Malhi GS, Kohlmann K, Jeavons S, Schapkaitz I, Anderson-Hunt M, Berk M (2011) N -acetylcysteine for major depressive episodes in bipolar disorder

When were GLP-1 drugs first approved for weight loss