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In a study on animals with joint arthritis, researchers discovered that using NSAIDs after injections made the cell treatment less effective

Due to their selective enhancement of certain beneficial gut bacteria and their ability to modify the composition and function of the gut microbiota, prebiotics are considered a potential supportive treatment for various disorders such as IBS, Crohns disease, issues with bowel motility, autism, obesity, and colorectal cancer [92]

However, not everyone will experience these side effects and some people tolerate one medication better than the other

University of California Davis Health System

So I know kind of what afflicts me