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As a result, oxidative stress activates inflammatory pathways, leading to the transformation of a normal cell into a tumor cell, increasing tumor cell survival, proliferation, chemoresistance/radioresistance, invasion, and angiogenesis 82

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The study confirmed that FOXO4-DRI binds directly to the disordered p53 TAD2 domain and forms a transiently folded complex a disordered-to-ordered transition involving both the FOXO4-derived region of the DRI peptide and its cationic cell permeability element

Glutathione plays a critical role in balancing that stress and supporting smooth, healthy sperm production