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Managed-care policies continue to whittle away at the amount of time spent by physicians with their patients, and it is understandable that a patient with routine complaints of fatigue and widespread pain could be summarily dismissed by the busy primary care physician as having FMS

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Free radicals can damage the collagen and elastin in the skin, leading to a loss of elasticity

10.1016/s0021-9258(18)47969-0 20 BergC

NICE guidance recommends urgent referral for lymphadenopathy with concerning features to exclude serious underlying pathology including malignancy