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In the MVP cohort 20 , rs10305420 is associated significantly with BMI-associated traits ( P value around 2 10 15 ), although it is in linkage with an upstream association (Extended Data Fig
Adjustments are made when needed, not as a reaction to impatience but as part of a thoughtful, long-term strategy aimed at achieving meaningful and lasting success
The class has been shown to have a direct myocardial effect, decrease postprandial lipemia and reduce BP
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In sensitivity analysis, we also included an isoform of l-carnitine, acetyl-carnitine, proxied by three genetic variants reaching genome-wide significance from the same GWAS as l-carnitine [20]
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