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Although more PD models are needed to validate whether PKM2 is a universal therapeutic target in PD, our results provide preliminary evidence that dimerizing PKM2 is a potential therapeutic approach to protect nigral dopaminergic neurons from oxidative damage

The eMTD peptide (KLNFRQKLLNLISKLFCSGT), consisting of the BH3 domain and mitochondrial targeting domain of the Noxa protein, causes cell membrane damage and necrotic cell death by interacting with voltage-dependent anion channel 2 63

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Although we need human studies to conclude with any certainty, taking certain probiotic strains could theoretically help improve histamine intolerance 13

Curr Opin Toxicol 7:95101 Baali A, Belhsen OK, Ouazzani KC, Amenzoui K, Yahyaoui A (2021) Ovarian histology of Sardinella aurita