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[10] SURMOUNT-1 : Tirzepatide for the treatment of obesity produced ~2022% weight loss over 72 weeks, among the largest effects seen in pharmacologic obesity treatment

Some practitioners recommend 5-10mg in the first week or two, then reducing to 2-5mg weekly thereafter

Similarly, a retrospective cohort trial, published in 2025, which included over 295,000 patients from North America, reported GLP1RA use was associated with about a 70% lower risk of incident dementia vs nonuse (HR = 0.30), significant even after statistical matching and multivariable adjustments [20]

10.1002/hep.20948 43 LeBlancA.ShiaoT

Aus diesem Grund muss in solchen Fllen der Blutzuckerspiegel regelmig kontrolliert werden, damit die Dosierung von blutzuckersenkenden Arzneimitteln entsprechend korrigiert werden kann