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only 18% of patients in Europe, 17% in Poland, and only 13% in Central and Eastern European countries achieve the therapeutic goal for very high-risk patients ( 190 mg/dl)

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The ratio of CP/CI-AMPAR expression covaried with the expression of NMDARs, forming a continuum from synapses with mostly CP-AMPARs and weaker and slower NMDAR-mediated components to synapses with mostly CI-AMPARs but a strong and fast NMDAR component (Bischofberger and Jonas, 2002

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