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10.1371/journal.pone.0152034 Summary Keywords disease susceptibility, gene mutation, hereditable disease, phosphotyrosine, posttranslational modification, signal transduction, single nucleotide polymorphism Citation Hendriks WJAJ, van Cruchten RTP and Pulido R (2023) Hereditable variants of classical protein tyrosine phosphatase genes: Will they prove innocent or guilty