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Exposure per milligram is higher, particularly in lighter East Asian users, while the smaller fat reserve makes a 75:25 fat-to-lean split more consequential

This reflects a shift toward non-surgical aesthetic treatments, with GLP-1 medications contributing to overall industry growth

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Originally developed as a tanning agent (acting via MC1R receptors), it also binds to melanocortin receptors in the brain (particularly MC3R and MC4R) that influence sexual function

Quantification of analytes was performed using an Agilent Technologies G6490 triple quadrupole mass spectrometer