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Its key research differentiator is selectivity preclinical data shows GH release without significant elevation of cortisol, prolactin, or ACTH, unlike GHRP-2 and GHRP-6

Oncogene (2014) 34(9):117484.10.1038/onc.2014.50 61 IacovazzoDCarlsenELugliFChiloiroSPiacentiniSBianchiAet alFactors predicting pasireotide responsiveness in somatotroph pituitary adenomas resistant to first generation somatostatin analogues: an immunohistochemical study

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Further, researchers should note that due to their upregulation of GH and IGF-1, GH secretagogues in general may accelerate disease progression in subjects with malignancies