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Formation of hexa- and decadepsipeptides via NRPS misoperation is key to form the isocereulides E, F and G, whereas peptide assembly in the biosynthesis of isocereulides A-D corresponds well to that of cereulide differing that L- O -Val is substituted by L- O -Leu (isocereulide A), L-Val by L-Ala (isocereulide D), D-Ala by D-Ser (isocereulide C) and D-O-Leu by D-O-Val (isocereulide B) due to a relaxed substrate specificity of the A domains and/or an inefficient proof reading by CesT

What good evidence would actually look like It is worth being concrete about what would move any of these peptides from forum legend to real cognitive medicine, because the bar is not mysterious

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While tracking bpc 157 and tb 500 benefits , investigators note that BPC-157 triggers the vessel-sprouting signals, while the actin mobilization from the tb 500 peptide helps smooth muscle cells stabilize the newly formed capillary walls