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Activation of TRPV1 restored GPX4 levels, reduced lipid peroxidation, and improved cartilage integrity in both IL-1treated chondrocytes and OA mouse models ( These findings highlight the importance of considering cellular heterogeneity in ferroptosis regulation and suggest that targeting ferroptosis in a subpopulation-specific manner may enhance therapeutic precision in OA

H., Hu, X., Li, H., Tieri, D., Zhang, H

The crystals of both types contained two copies of the hTrxR1hTrx1 complex in the asymmetric unit thereby maintaining the usual hTrxR1 dimer

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[DOI] [PMC free article] [PubMed] [Google Scholar] 297.Gow N, Netea M, Munro CA, Ferwerda G, Bates S, Mora-Montes H, Walker LA, Jansen T, Jacobs L, Tsoni V, Brown G, Odds FC, Van der Meer JW, Brown A, Kullberg BJ