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Genuine KLOW-mediated cognitive enhancement requires 20+ minutes for the peptide to reach CNS targets, bind receptors, and trigger downstream signaling cascades

Abstract Providing NO-system importance, we suggest that one single application of the NOS-blocker L-NAME may induce retinal ischemia in rats, and that the stable pentadecapeptide BPC 157 may be the therapy, since it may interact with the NO-system and may counteract various adverse effects of L-NAME application

Investigation 108, 11671174