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Metabolomics-based research may further reveal valuable biomarkers for therapy monitoring, as the reprogramming of ammonium metabolism in prostate cancer generates a range of intermediate metabolites, such as polyamines, citrate, and various amino acids, as well as key metabolic enzymes, which hold promise as indicators of therapeutic response (284)

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10.1016/0092-8674(94)90217-8 56 GullnerG.FodorJ.KirlyL

Prolonged misuse of acetaminophen-opioid combinations or excessive alcohol consumption alongside acetaminophen results in irreversible organ damage, respiratory depression, and fatal overdoses

Kidney injury was assessed using serum creatinine laboratory values