glp 1 metabolic syndrome GLP-1 for Weight Loss and Diabetes Positive impact of GIP, GLP-1

Based on data from RCTs in T1D and those with patients with T2D, initiation of a GLP-1RA should be followed by a decrease of total insulin dose to reduce events of hypoglycemia (71)

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The enhanced efficacy profile potentially reduces treatment duration and improves patient compliance, translating to better therapeutic value propositions

The FDA does not currently have guidelines on microdosing GLP-1 medications and its clear that more study is needed to understand the risks, benefits, and efficacy of doses that are lower than those recommended by current prescription guidelines

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